See our Healthy Travel Information page for the latest information on openings, guidelines, and COVID-19 updates. Masks are no longer required across Coastal Mississippi. All are encouraged to follow safety guidelines outlined by the Mississippi State Department of Health. The Mississippi Gaming Commission is requiring all guests in casinos wear masks.

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Greyhound Bus Lines

Biloxi/Gulfport Stations, Coastwide, MS 39530
(800) 231-2222

Greyhound Lines, Inc. services more than 2,300 destinations with 13,000 daily departures across North America. It has become an American icon, providing safe, enjoyable, and affordable travel to nearly 25 million passengers each year. The Greyhound running dog is one of the most-recognized brands in the world. 

Greyhound offers two station locations on the MS Gulf Coast:
• Biloxi: 820 Martin Luther King Blvd - (228) 436-4335
• Gulfport: Clark Convenience Store, 10015 HWY 49 - (228) 863-1022