Gulf Coast, Mississippi
This under-the-radar gem is as warm and welcoming as it is laidback, making it ideal for a weekend escape with your friends. If you and your friends enjoy wandering sans agenda, start out in Fishbone Alley, a funky walkway with colorful artwork and string lights as you weave your way towards Pop Brothers for a refreshing, small-batch popsicles made with herbs, spices, and fresh fruit from local producers. Make a detour to The Greenhouse on Porter for yoga, a dance party, or even a 7- or 8-mile bike ride known by locals as the "Porter Pedal." Accommodations-wise, you can't do better than the supremely chic White House Hotel, where Cora's will spoil you and your girls with a selection of 40 wines and 16 beers on tap. P.S. You'll find it especially hard to pry yourself out of the hot tub — it's got ocean views.
For more information visit gulfcoast.org.